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Hans Ernst August Buchner

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Hans Ernst August Buchner

Hans Buchner
Hans Ernst August Buchner
Born 16 December 1850
Munich, German Confederation
Died 5 April 1902
Munich, German Empire
Nationality Germany
Institutions Munich University
Alma mater University of Leipzig
Known for Discovering complement
Work on Gamma globulin
Study of Anaerobic organisms

Hans Ernst August Buchner (December 16, 1850 – April 5, 1902) was a German bacteriologist who was born and raised in Munich. He was the older brother of Eduard Buchner (1860–1917), winner of the 1907 Nobel Prize in Chemistry.

He studied medicine in Munich and Leipzig, earning his MD from the University of Leipzig in 1874, and afterwards serving as a physician in the Bavarian Army. In 1880 be became a lecturer at the University of Munich, where he worked under Max von Pettenkofer (1818–1901) and was an associate to Max von Gruber (1853–1927). In Munich he was also director of the institute of hygiene.

Hans Buchner was a pioneer in the field of immunology. He was the first to discover a substance in blood serum that was capable of destroying bacteria. He called the substance "alexin", which was later named "complement" by Paul Ehrlich (1854–1915).

In 1888 he introduced the pyrogallic method for cultivation of anaerobic bacteria.[1][2] Also, with Martin Hahn, he assisted his brother, Eduard Buchner, with the isolation of zymase. Their findings were published in a 1903 treatise titled Die Zymasegärung (Zymase fermentation).[3]

Selected writings

  • Die ätiologische Therapie und Prophylaxe der Lungentuberculose. (Aetiological therapy and prophylaxis involving lung tuberculosis); (1883)
  • Über die bakterientödtende Wirkung des zellenfreien Blutserums (On the bacteriological effects of cell-free blood serum); (1889)
  • Die Zymasegärung : Untersuchungen über den Inhalt der Hefezellen und die biologische Seite des Gärungsproblems (with Eduard Buchner and Martin Hahn, 1903) - Zymase fermentation : Studies on the content of yeast cells and the biological side of the fermentation problem.[4]



External links

  • A Simple Way of using Buchner's Method for the Cultivation of Anaërobic Bacteria NCBI J Med Res. 1906 July; 15(1): 113–116.1
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